HLTF Rabbit Monoclonal Antibody [Clone ID: R03-1E4]
Other products for "HLTF"
Specifications
Product Data | |
Clone Name | R03-1E4 |
Applications | IF, WB |
Recommended Dilution | WB: 1/2000-1/10000 ICC/IF: 1/20 |
Reactivities | Human |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human HLTF |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | Calculated MW: 114 kDa; Observed MW: 114 kDa |
Gene Name | helicase-like transcription factor |
Database Link | |
Background | Swiss-Prot Acc.Q14527.Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters . These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. |
Synonyms | HIP116; HIP116A; HLTF1; RNF80; SMARCA3; SNF2L3; ZBU1 |
Reference Data |
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