Heme Oxygenase 1 (HMOX1) Rabbit Monoclonal Antibody [Clone ID: R02-6C1]

CAT#: TA384444

Heme Oxygenase 1 Rabbit monoclonal Antibody

Product Images

Western blot detection of Heme Oxygenase 1 in Mouse spleen lysates using Heme Oxygenase 1 Rabbit mAb(1:1000 diluted).Predicted band size:33KDa.Observed band size:33KDa.

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  Western blot detection of Heme Oxygenase 1 in U251MG,K562,A549 cell lysates using Heme Oxygenase 1 Rabbit mAb(1:500 diluted).Predicted band size:33kDa.Observed band size:33kDa.

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  Immunohistochemistry of Heme Oxygenase 1 in paraffin-embedded Human lung cancer tissue using Heme Oxygenase 1 Rabbit mAb at dilution 1/5

Specifications

Product Data

• Clone Name: R02-6C1
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/50
  ICC/IF: 1/50
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of mouse Heme Oxygenase 1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 33 kDa; Observed MW: 33 kDa
• Gene Name: heme oxygenase 1
• Database Link:
  Entrez Gene 3162 Human
  UniProt ID P09601
• Background: Swiss-Prot Acc.P09601.Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
• Synonyms: bK286B10; HO; HO-1; HO1; HSP32