hnRNP K (HNRNPK) Rabbit Polyclonal Antibody

CAT#: TA384446

hnRNP K Rabbit polyclonal Antibody

Product Images

Western blot detection of hnRNP K in HepG2,3T3,HUVEC,NTERA2,Hela cell lysates using hnRNP K Rabbit pAb(1:1000 diluted).Predicted band size:60kDa.Observed band size:60kDa.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human hnRNP K
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 60kDa
• Gene Name: heterogeneous nuclear ribonucleoprotein K
• Database Link:
  Entrez Gene 3190 Human
  UniProt ID P61978
• Background: Swiss-Prot Acc.P61978.Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.
• Synonyms: CSBP; FLJ41122; HNRPK; OTTHUMP00000021554; OTTHUMP00000021558; TUNP