IL17RC Rabbit Polyclonal Antibody

CAT#: TA384517

IL-17 Receptor C Rabbit polyclonal Antibody

Product Images

Western Blot analysis of various cells using IL-17RC Polyclonal Antibody

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  Western Blot analysis of HuvEc cells using IL-17RC Polyclonal Antibody

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  Western blot analysis of the lysates from RAW264.7cells using IL17RC antibody.

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: WB: 1/500-1/2000
  ELISA: 1/20000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human IL17RC. AA range:721-770
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):70
• Database Link:
  UniProt ID Q8NAC3
• Background: Swiss-Prot Acc.Q8NAC3.Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495).