CD41 (ITGA2B) Mouse Monoclonal Antibody [Clone ID: 9G4-3F4-10B8]

CAT#: TA384552

Integrin alpha Iib (9G4) Mouse monoclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded Human-breast-cancer tissue. 1,CD41 Monoclonal Antibody(Q90) was diluted at 1:200(4°C,overnight). 2, Sodium citrate pH 6.0 was used for antibody retrieval(>98°C,20min). 3,Secondary antibody was diluted at 1:200(room tempeRature, 30min). Negative control was used by secondary antibody only.

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  Immunohistochemical analysis of paraffin-embedded Human Spleen using CD41 Mouse mAb diluted at 1:200.

Specifications

Product Data

• Clone Name: 9G4-3F4-10B8
• Applications: IHC
• Recommended Dilution: IHC: 1/100
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic Peptide of CD41
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Gene Name: integrin subunit alpha 2b
• Database Link:
  Entrez Gene 3674 Human
  UniProt ID P08514
• Background: Swiss-Prot Acc.P08514.Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha-IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface.RegionsFeature keyPosition(s)Description
• Synonyms: CD41; CD41B; GP2B; GPIIb; GTA; HPA3; ITGAB