LEF1 Rabbit Polyclonal Antibody

CAT#: TA384655

LEF1 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human spleen, using LEF1 Antibody.

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  Western blot analysis of LEF1 expression in Jurkat cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human LEF1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 44kDa
• Gene Name: lymphoid enhancer binding factor 1
• Database Link:
  Entrez Gene 51176 Human
  UniProt ID Q9UJU2
• Background: Swiss-Prot Acc.Q9UJU2.Participates in the Wnt signaling pathway. Activates transcription of target genes in the presence of CTNNB1 and EP300. May play a role in hair cell differentiation and follicle morphogenesis. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1. Regulates T-cell receptor alpha enhancer function. Binds DNA in a sequence-specific manner. PIAG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (By similarity).
• Synonyms: DKFZp586H0919; FLJ46390; LEF-1; TCF1-alpha; TCF1ALPHA