Galectin 3 (LGALS3) Rabbit Monoclonal Antibody [Clone ID: R05-8J4]

CAT#: TA384662

Galectin 3 Rabbit monoclonal Antibody

Product Images

Western blot detection of Galectin 3 in 3T3,Hela cell lysates using Galectin 3 Rabbit mAb(1:1000 diluted).Predicted band size:26kDa.Observed band size:28kDa.

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  Immunohistochemistry of Galectin 3 in paraffin-embedded Human colon cancer tissue using Galectin 3 Rabbit mAb at dilution 1/50

Specifications

Product Data

• Clone Name: R05-8J4
• Applications: IHC, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/2000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Galectin 3
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 26 kDa; Observed MW: 28 kDa
• Gene Name: lectin, galactoside binding soluble 3
• Database Link:
  Entrez Gene 3958 Human
  UniProt ID P17931
• Background: Swiss-Prot Acc.P17931.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis . In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.
• Synonyms: CBP35; GAL3; GALBP; GALIG; L-31; LGALS2; MAC-2; MAC2