MAGEA3 Rabbit Monoclonal Antibody [Clone ID: R07-8A2]

CAT#: TA384693

MAGEA3 Rabbit monoclonal Antibody

Product Images

Western blot detection of MAGEA3 in Hela cell lysates using MAGEA3 Rabbit mAb(1:1000 diluted).Predicted band size:35kDa.Observed band size:45kDa.

Specifications

Product Data

• Clone Name: R07-8A2
• Applications: WB
• Recommended Dilution: WB: 1/1000
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human MAGEA3
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 35 kDa; Observed MW: 45 kDa
• Gene Name: MAGE family member A3
• Database Link:
  Entrez Gene 4102 Human
  UniProt ID P43357
• Background: Swiss-Prot Acc.P43357.Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
• Synonyms: CT1.3; HIP8; HYPD; MAGE3; MAGEA6; MGC14613