MAPK6 Rabbit Monoclonal Antibody [Clone ID: R04-5B8]

CAT#: TA384738

MAPK6 Rabbit monoclonal Antibody

Specifications

Product Data

• Clone Name: R04-5B8
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20-1/100
  IP: 1/20
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human MAPK6
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 83 kDa; Observed MW: 105 kDa
• Gene Name: mitogen-activated protein kinase 6
• Database Link:
  Entrez Gene 5597 Human
  UniProt ID Q16659
• Background: Swiss-Prot Acc.Q16659.Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle .
• Synonyms: DKFZp686F03189; ERK-3; ERK3; HsT17250; p97-MAPK; p97MAPK; PRKM6