MLKL Mouse Monoclonal Antibody [Clone ID: 5E3-6B4-7G9]

CAT#: TA384783

MLKL (5E3) Mouse monoclonal Antibody

Specifications

Product Data

• Clone Name: 5E3-6B4-7G9
• Applications: IHC
• Recommended Dilution: IHC: 1/100-200
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Synthetic peptide conjugated to KLH.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 54kDa
• Gene Name: mixed lineage kinase domain-like
• Database Link:
  Entrez Gene 197259 Human
  UniProt ID Q8NB16
• Background: Swiss-Prot Acc.Q8NB16.Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
• Synonyms: FLJ34389