MTOR Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | WB: 1/500-1/1000 |
Reactivities | Human, Mouse, Pig |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human Phospho-mTOR (S2448) (Phosphorylated) |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | 289kDa |
Gene Name | mechanistic target of rapamycin |
Database Link | |
Background | Swiss-Prot Acc.P42345.An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. |
Synonyms | FLJ44809; FRAP; FRAP1; FRAP2; KIAA1303; RAFT1; RAPT1; RAPTOR; RPTOR |
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