NFkB p100 / p52 (NFKB2) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | IF, IP, WB |
Recommended Dilution | WB: 1/1000-1/5000 ICC/IF: 1/50-1/200 IP: 1/50 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | A synthesized peptide derived from human NFkB p100 / p52 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | Affinity Chromatography |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | 120,52kDa |
Gene Name | nuclear factor kappa B subunit 2 |
Database Link | |
Background | Swiss-Prot Acc.Q00653.Transcription factors of the nuclear factor κ B (NF-κB)/Rel family play a pivotal role in inflammatory and immune responses. NF-κB-activating agents can induce the phosphorylation of IκB proteins, targeting them for rapid degradation through the ubiquitin-proteasome pathway and releasing NF-κB to enter the nucleus where it regulates gene expression. |
Synonyms | H2TF1; LYT-10; LYT10; OTTHUMP00000020371; p52 |
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