eNOS (NOS3) Mouse Monoclonal Antibody [Clone ID: 2E8-5A5-7B1]

CAT#: TA384881

eNOS (2E8) Mouse monoclonal Antibody

Specifications

Product Data

• Clone Name: 2E8-5A5-7B1
• Applications: WB
• Recommended Dilution: WB: 1/500-2000
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Protein of eNOS
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):130
• Gene Name: nitric oxide synthase 3
• Database Link:
  Entrez Gene 4846 Human
  UniProt ID P29474
• Background: Swiss-Prot Acc.P29474.Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets.Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.
• Synonyms: cNOS; EC-NOS; ECNOS; eNOS; NOSIII