TrkA (NTRK1) Rabbit Polyclonal Antibody

CAT#: TA384901

Trk Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded mouse brain, using TrkA+B+C Antibody.

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  Immunofluorescent analysis of Neuro-2a cells, using TrkA+B+C Antibody.

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  Western blot analysis of TrkA+B+C expression in Human fetal brain lysate.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/1000-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human TrkA+B+C
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 140kDa
• Gene Name: neurotrophic receptor tyrosine kinase 1
• Database Link:
  Entrez Gene 4914 Human
  UniProt ID P04629
• Background: Swiss-Prot Acc.P04629,Q16288,Q16620.The family of Trk receptor tyrosine kinases consists of TrkA, TrkB, and TrkC. While the sequence of these family members is highly conserved, they are activated by different neurotrophins: TrkA by NGF, TrkB by BDNF or NT4, and TrkC by NT3. Neurotrophin signaling through these receptors regulates a number of physiological processes, such as cell survival, proliferation, neural development, and axon and dendrite growth and patterning.
• Synonyms: DKFZp781I14186; MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA