PARK7 Rabbit Polyclonal Antibody

CAT#: TA384930

PARK7/DJ1 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human bladder cancer, using PARK7 Antibody.

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  Western blot analysis of PARK7 expression in HeLa cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/20
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human PARK7
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 20kDa
• Gene Name: Parkinsonism associated deglycase
• Database Link:
  Entrez Gene 11315 Human
  UniProt ID Q99497
• Background: Swiss-Prot Acc.Q99497.Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. It cooperates with Ras to increase cell transformation, it positively regulates transcription of the androgen receptor, and it may function as an indicator of oxidative stress.
• Synonyms: DJ-1; DJ1; FLJ27376; FLJ34360; FLJ92274; OTTHUMP00000001350; OTTHUMP00000001351