Myosin Phosphatase (PPP1R12A) Rabbit Polyclonal Antibody

CAT#: TA385025

Myosin Phosphatase Rabbit polyclonal Antibody

Product Images

Western Blot analysis of various cells using MYPT1 Polyclonal Antibody diluted at 1：2000

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  Western Blot analysis of 293T cells using MYPT1 Polyclonal Antibody diluted at 1：2000

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  Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using MYPT1 Antibody. The picture on the right is blocked with the synthesized peptide.

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  Western blot analysis of lysates from COS7 cells, using MYPT1 Antibody. The lane on the right is blocked with the synthesized peptide.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/100-1/300
  ELISA: 1/5000
• Reactivities: Human, Monkey, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The antiserum was produced against synthesized peptide derived from human MYPT1. AA range:661-710
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):140
• Gene Name: protein phosphatase 1 regulatory subunit 12A
• Database Link:
  Entrez Gene 4659 Human
  UniProt ID O14974
• Background: Swiss-Prot Acc.O14974.Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.
• Synonyms: MBS; MGC133042; MYPT1