Peroxiredoxin 1 (PRDX1) Mouse Monoclonal Antibody [Clone ID: 6A6-4H3-7A3]

CAT#: TA385032

Peroxiredoxin 1 (6A6) Mouse monoclonal Antibody

Product Images

Western blot detection of Prdx 1 in T47D,3T3,COS7,C6 and Hela cell lysates using Prdx 1 mouse mAb (1:3000 diluted).Predicted band size:21kDa.Observed band size:21kDa.

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  IF analysis of Hela with antibody (Left) and DAPI (Right) diluted at 1:100.

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  Western blot analysis of 1) MCF7, 2) Rat Kidney Tissue, 3) Mouse Brain Tissue, diluted at 1:2000.

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  Western blot detection of Peroxiredoxin 1/Prdx1 in Jurkat,CHO-K1,C6,Hela cell lysates using Peroxiredoxin 1/Prdx1 (6A6) Mouse mAb(1:1000 diluted).Predicted band size:21KDa.Observed band size:21KDa.

Specifications

Product Data

• Clone Name: 6A6-4H3-7A3
• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/1000-3000
  ICC: 1/100-200
  IHC: 1/50-300
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant Protein of Peroxiredoxin-1
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Observed MW (kDa):21
• Gene Name: peroxiredoxin 1
• Database Link:
  Entrez Gene 5052 Human
  UniProt ID Q06830
• Background: Swiss-Prot Acc.Q06830.Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H2O2 (PubMed:9497357). Reduces an intramolecular disulfide bond in GDPD5 that gates the ability to GDPD5 to drive postmitotic motor neuron differentiation .
• Synonyms: MSP23; NKEF-A; NKEFA; PAG; PAGA; PAGB; PRX1; PRXI; TDPX2