Prostaglandin D Synthase (PTGDS) Rabbit Monoclonal Antibody [Clone ID: R06-1C5]

CAT#: TA385080

Prostaglandin D Synthase Rabbit monoclonal Antibody

Product Images

Western blot detection of Prostaglandin D Synthase in K562,C6,3T3,Hela cell lysates using Prostaglandin D Synthase Rabbit mAb(1:1000 diluted).Predicted band size:21kDa.Observed band size:26kDa.

Specifications

Product Data

• Clone Name: R06-1C5
• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/20
  ICC/IF: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human Prostaglandin D Synthase
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 21 kDa; Observed MW: 26 kDa
• Gene Name: prostaglandin D2 synthase
• Database Link:
  Entrez Gene 5730 Human
  UniProt ID P41222
• Background: Swiss-Prot Acc.P41222.Catalyzes the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation. Involved in a variety of CNS functions, such as sedation, NREM sleep and PGE2-induced allodynia, and may have an anti-apoptotic role in oligodendrocytes. Binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. Possibly involved in development and maintenance of the blood-brain, blood-retina, blood-aqueous humor and blood-Tis barrier. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system.
• Synonyms: Cerebrin-28; L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2