FAK (PTK2) Rabbit Polyclonal Antibody

CAT#: TA385089

FAK Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded mouse spleen, using FAK Antibody.

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  Immunofluorescent analysis of Hela cells, using FAK Antibody.

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  Western blot analysis of FAK expression in HeLa cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/30
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human FAK
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 119kDa
• Gene Name: protein tyrosine kinase 2
• Database Link:
  Entrez Gene 5747 Human
  UniProt ID Q05397
• Background: Swiss-Prot Acc.Q05397.This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix.
• Synonyms: FADK; FAK; FAK1; FRNK; pp125FAK