Rab5 (RAB5A) Rabbit Polyclonal Antibody

CAT#: TA385105

Rab5 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human colon, using Rab5 Antibody.

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  Western blot analysis of Rab5 expression in MCF-7 cell lysate.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Rab5
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 24kDa
• Gene Name: RAB5A, member RAS oncogene family
• Database Link:
  Entrez Gene 5868 Human
  UniProt ID P20339
• Background: Swiss-Prot Acc.P20339.Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis.
• Synonyms: RAB5