RAP1A Rabbit Monoclonal Antibody [Clone ID: R03-7H8]
Other products for "RAP1B"
Specifications
Product Data | |
Clone Name | R03-7H8 |
Applications | IP, WB |
Recommended Dilution | WB: 1/2000-1/10000 IP: 1/20 |
Reactivities | Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human RAP1A/B |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | Calculated MW: 21 kDa; Observed MW: 21 kDa |
Gene Name | RAP1A, member of RAS oncogene family |
Database Link | |
Background | Swiss-Prot Acc.P61224.GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function. |
Synonyms | C21KG; G-22K; KREV-1; KREV1; OTTHUMP00000013741; RAP1; SMGP21 |
Reference Data |
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