RbAp48 (RBBP4) Rabbit Monoclonal Antibody [Clone ID: R07-5D6]

CAT#: TA385142

RBBP4 Rabbit monoclonal Antibody

Product Images

Western blot detection of RbAp48 in Hela cell lysates using RbAp48 Rabbit mAb(1:1000 diluted).Predicted band size:48KDa.Observed band size:48KDa.

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  Western blot detection of RbAp48 in Hela,CHO-K1,C6,Jurkat cell lysates using RbAp48 Rabbit mAb(1:500 diluted).Predicted band size:48kDa.Observed band size:48kDa.

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  Immunohistochemistry of RbAp48 in paraffin-embedded Human lung cancer tissue using RbAp48 Rabbit mAb at dilution 1/2

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  Immunocytochemistry of RbAp48(green) in Hela cells using RbAp48 Rabbit mAb at dilution 1/50, and DAPI(blue)

Specifications

Product Data

• Clone Name: R07-5D6
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/2000-1/10000
  IHC: 1/20
  ICC/IF: 1/20
  IP: 1/20
• Reactivities: Hamster, Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human RbAp48
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 48 kDa; Observed MW: 48 kDa
• Gene Name: RB binding protein 4, chromatin remodeling factor
• Database Link:
  Entrez Gene 5928 Human
  UniProt ID Q09028
• Background: Swiss-Prot Acc.Q09028.Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome remodeling; the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome remodeling factor) complex.
• Synonyms: NURF55; RBAP48; RBBP-4