RSK1 p90 (RPS6KA1) Rabbit Polyclonal Antibody

CAT#: TA385184

Phospho-RSK1 p90 (Thr359/Ser363) Rabbit polyclonal Antibody

Product Images

Western blot analysis of RSK 1 p90 phosphorylation expression in K562 cell lysate treated with EGF.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Phospho-RSK1 p90 (T359+S363) (Phosphorylated)
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 90kDa
• Gene Name: ribosomal protein S6 kinase A1
• Database Link:
  Entrez Gene 6195 Human
  UniProt ID Q15418
• Background: Swiss-Prot Acc.Q15418.Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.
• Synonyms: HU-1; MAPKAPK1A; p90S6K; pp90RSK1; RSK; RSK-1; RSK1