RUNX2 Rabbit Polyclonal Antibody

CAT#: TA385195

RUNX Rabbit polyclonal Antibody

Product Images

Western blot analysis of RUNX1/RUNX2/RUNX3 expression in Raji and Jurkat cell lysates using RUNX1/RUNX2/RUNX3 antibody at 1/5000 dilution.Predicted band size:51KDa.Observed band size:51KDa.

• 

  Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MCF7,Hela and Molt-4 cell lysates using RUNX1/RUNX2/RUNX3 antibody at 1/5 dilution.Predicted band size:51KDa.Observed band size:51KDa.

• 

  Western blot analysis of RUNX1/RUNX2/RUNX3 expression in MOLT4 cell lysate.

• 

  Immunohistochemical analysis of paraffin-embedded mouse lung, using RUNX1/RUNX2/RUNX3 Antibody.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human RUNX1/RUNX2/RUNX3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 51kDa
• Gene Name: runt related transcription factor 2
• Database Link:
  Entrez Gene 860 Human
  UniProt ID Q01196
• Background: Swiss-Prot Acc.Q01196,Q13761,Q13950.RUNX2 regulates the transcription of various genes including osteopontin, bone sialoprotein, and osteocalcin via binding to the core site of the enhancers or promoters.RUNX3/AML2 is a member of the Runt family of transcription factors. RUNX3 is important for the suppression of cell proliferation in the gastric epithelium, neurogenesis of the dorsal root ganglia, and T cell differentiation.
• Synonyms: AML3; CBF-alpha-1; CBFA1; CCD; CCD1; MGC120022; MGC120023; OSF-2; OSF2; PEA2aA; PEBP2A; PEBP2A1; PEBP2A2; PEBP2aA; PEBP2aA1