S100 beta (S100B) Rabbit Monoclonal Antibody [Clone ID: R01-1F9]

CAT#: TA385204

S100B Rabbit monoclonal Antibody

Product Images

Western blot detection of S100 beta in Rat Brain lysates using S100 beta Rabbit mAb(1:1000 diluted).Predicted band size:11KDa.Observed band size:11KDa.

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  Western blot detection of S100 beta in Rat Brain lysates using S100 beta Rabbit mAb(1:500 diluted).Predicted band size:11kDa.Observed band size:11kDa.

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  Immunohistochemistry of S1 beta in paraffin-embedded Human breast cancer tissue using S1 beta Rabbit mAb at dilution 1/5

Specifications

Product Data

• Clone Name: R01-1F9
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/50-1/200
  IP: 1/20
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human S100 beta
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 11 kDa; Observed MW: 11 kDa
• Gene Name: S100 calcium binding protein B
• Database Link:
  Entrez Gene 6285 Human
  UniProt ID P04271
• Background: Swiss-Prot Acc.P04271.Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
• Synonyms: NEF; OTTHUMP00000174958; S100; S100beta