SATB2 Rabbit Polyclonal Antibody

CAT#: TA385208

SATB2 Rabbit polyclonal Antibody

Product Images

Western blot analysis of SATB2 expression in HT-1080 cell lysate.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human SATB2
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 83kDa
• Gene Name: SATB homeobox 2
• Database Link:
  Entrez Gene 23314 Human
  UniProt ID Q9UPW6
• Background: Swiss-Prot Acc.Q9UPW6.Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.
• Synonyms: FLJ21474; FLJ32076; KIAA1034; MGC119474; MGC119477; OTTHUMP00000163655; OTTHUMP00000205774; OTTHUMP00000205775