SCARB1 Rabbit Monoclonal Antibody [Clone ID: R07-4H3]

CAT#: TA385211

SCARB1 Rabbit monoclonal Antibody

Product Images

Western blot detection of Scavenging Receptor SR-BI in 3T3,Hela cell lysates using Scavenging Receptor SR-BI Rabbit mAb(1:1000 diluted).Predicted band size:61kDa.Observed band size:80kDa.

Specifications

Product Data

• Clone Name: R07-4H3
• Applications: IP, WB
• Recommended Dilution: WB: 1/1000
  IP: 1/20
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human Scavenging Receptor SR-BI
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 61 kDa; Observed MW: 80 kDa
• Gene Name: scavenger receptor class B member 1
• Database Link:
  Entrez Gene 949 Human
  UniProt ID Q8WTV0
• Background: Swiss-Prot Acc.Q8WTV0.Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218).
• Synonyms: CD36L1; CLA-1; CLA1; MGC138242; SR-BI; SRB1