SCD1 (SCD) Rabbit Monoclonal Antibody [Clone ID: R04-2K1]

CAT#: TA385212

SCD1 Rabbit monoclonal Antibody

Product Images

Western blot detection of SCD1 in Hela cell lysates using SCD1 Rabbit mAb(1:1000 diluted).Predicted band size:42kDa.Observed band size:37kDa.

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  Immunocytochemistry of SCD1(green) in Hela cells using SCD1 Rabbit mAb at dilution 1/50, and DAPI(blue)

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  Immunohistochemistry of SCD1 in paraffin-embedded Human lung cancer tissue using SCD1 Rabbit mAb at dilution 1/5

Specifications

Product Data

• Clone Name: R04-2K1
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000
  IHC: 1/200
  ICC/IF: 1/20-1/100
  IP: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human SCD1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 42 kDa; Observed MW: 37 kDa
• Gene Name: stearoyl-CoA desaturase
• Database Link:
  Entrez Gene 6319 Human
  UniProt ID O00767
• Background: Swiss-Prot Acc.O00767.Stearyl-CoA desaturase that utilizes O2 and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates (PubMed:15907797, PubMed:18765284). Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA (PubMed:15907797, PubMed:18765284). Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids (PubMed:15610069). Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation . Plays an important role in body energy homeostasis . Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides .
• Synonyms: Delta(9)-desaturase; delta-9-desaturase; FADS5; MSTP008; SCD1; SCDOS