SFRP4 Rabbit Monoclonal Antibody [Clone ID: R01-2C2]

CAT#: TA385235

SFRP4 Rabbit monoclonal Antibody

Product Images

Western blot detection of SFRP4 in K562,3T3,Hela cell lysates using SFRP4 Rabbit mAb(1:1000 diluted).Predicted band size:40kDa.Observed band size:53-55kDa.

Specifications

Product Data

• Clone Name: R01-2C2
• Applications: WB
• Recommended Dilution: WB: 1/1000-1/5000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human SFRP4
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 40 kDa; Observed MW: 53-55 kDa
• Gene Name: secreted frizzled related protein 4
• Database Link:
  Entrez Gene 6424 Human
  UniProt ID Q6FHJ7
• Background: Swiss-Prot Acc.Q6FHJ7.Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types . SFRP4 plays a role in bone morphogenesis. May also act as a regulator of adult uterine morphology and function. May also increase apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling . Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (PubMed:12952927).
• Synonyms: FRP-4; FRPHE; MGC26498; sFRP-4