SIRT2 Mouse Monoclonal Antibody [Clone ID: 1D4-H11-H11]

CAT#: TA385246

SIRT2 (1D4) Mouse monoclonal Antibody

Product Images

Western blot detection of SirT2 in PC-12, Rat Brain and Mouse Brain cell lysates using SirT2 mouse mAb (1:1000 diluted). Predicted band size: 39,43KDa. Observed band size:39,43KDa.

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  Immunofluorescent analysis of Hela cells fixed fixed by anhydrous methanol at -20u2103 and using SirT2 (200474,dilution 1:50) mouse mAb (green) and Histone H3.1 (Phospho-Ser10) (310045,dilution 1:200) Rabbit pAb (red).

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  Western blot detection of SirT2 in Rat Cerebral Cortex and Rat Brain lysates using SirT2 mouse mAb (1:1000 diluted). Predicted band size: 39,43KDa. Observed band size:39,43KDa.

Specifications

Product Data

• Clone Name: 1D4-H11-H11
• Applications: IF, WB
• Recommended Dilution: WB: 1/1000
  ICC: 1/100
• Reactivities: Human, Mouse, Rat
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Purified recombinant human SirT2 protein expressed in E.coli.
• Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 43kDa
• Gene Name: sirtuin 2
• Database Link:
  Entrez Gene 22933 Human
  UniProt ID Q8IXJ6
• Background: Swiss-Prot Acc.Q8IXJ6.Participate in a variety of cellular functions, including histone deacetylation, gene silencing, chromosomal stability, and aging. SIRT2, a human homolog of the yeast SIR2, functions as transcriptional silencing mediator at mating-type loci, telomeres and ribosomal gene clusters. SIRT2 expression increases dramatically during mitosis and is multiply phosphorylated at the G(2)/M transition of the cell cycle.
• Synonyms: SIR2; SIR2-like; SIR2L; SIR2L2