SMC1 (SMC1A) Rabbit Polyclonal Antibody

CAT#: TA385286

SMC1A Rabbit polyclonal Antibody

Product Images

Western blot analysis of SMC1 expression in (1) HeLa cell lysate; (2) Jurkat cell lysate.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1/1000-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human SMC1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 143kDa
• Gene Name: structural maintenance of chromosomes 1A
• Database Link:
  Entrez Gene 8243 Human
  UniProt ID Q14683
• Background: Swiss-Prot Acc.Q14683.Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair. ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint.
• Synonyms: CDLS2; DKFZp686L19178; DXS423E; KIAA0178; MGC138332; SB1.8; SMC1; SMC1alpha; SMC1L1; SMCB