SNAP25 Rabbit Polyclonal Antibody

CAT#: TA385292

SNAP25 Rabbit polyclonal Antibody

Product Images

Western blot analysis of SNAP25 expression in SH-SY5Y cell lysate.

Specifications

Product Data

• Applications: IF, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human SNAP25
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 25kDa
• Gene Name: synaptosome associated protein 25kDa
• Database Link:
  Entrez Gene 6616 Human
  UniProt ID P60880
• Background: Swiss-Prot Acc.P60880.SNAP25 forms a core complex with the SNARE proteins syntaxin and synaptobrevin to mediate synaptic vesicle fusion with the plasma membrane during Ca2+-dependent exocytosis. This complex is responsible for exocytosis of the neurotransmitter γ-aminobutyric acid (GABA). Neurotransmitter release is inhibited by proteolysis of SNAP25 by botulinum toxins A and E. SNAP25 plays a secondary role as a Q-SNARE involved in endosome fusion; the protein is associated with genetic susceptibility to attention-deficit hyperactivity disorder (ADHD).
• Synonyms: bA416N4.2; dJ1068F16.2; FLJ23079; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP