SNRPD3 Rabbit Monoclonal Antibody [Clone ID: R09-8I7]
Other products for "SNRPD3"
Specifications
Product Data | |
Clone Name | R09-8I7 |
Applications | WB |
Recommended Dilution | WB: 1/1000-1/2000 |
Reactivities | Human, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human SNRPD3 |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Stability | 1 year |
Predicted Protein Size | Calculated MW: 14 kDa; Observed MW: 14 kDa |
Gene Name | small nuclear ribonucleoprotein D3 polypeptide |
Database Link | |
Background | Swiss-Prot Acc.P62318.Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing . |
Synonyms | OTTHUMP00000198382; Sm-D3; SMD3 |
Reference Data |
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