SNRPD3 Rabbit Monoclonal Antibody [Clone ID: R09-8I7]

CAT#: TA385295

SNRPD3 Rabbit monoclonal Antibody

Product Images

Western blot analysis of SNRPD3 in C6, Hela lysates using SNRPD3 antibody.

Specifications

Product Data

• Clone Name: R09-8I7
• Applications: WB
• Recommended Dilution: WB: 1/1000-1/2000
• Reactivities: Human, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of human SNRPD3
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 14 kDa; Observed MW: 14 kDa
• Gene Name: small nuclear ribonucleoprotein D3 polypeptide
• Database Link:
  Entrez Gene 6634 Human
  UniProt ID P62318
• Background: Swiss-Prot Acc.P62318.Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Is also a component of the minor U12 spliceosome (PubMed:15146077). As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing .
• Synonyms: OTTHUMP00000198382; Sm-D3; SMD3