TDP43 (TARDBP) Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | FC, IF, IHC, IP, WB |
| Recommended Dilution | WB: 1/500-1/2000 IHC: 1/50-1/200 ICC/IF: 1/50-1/200 IP: 1/50 FC: 1/200 |
| Reactivities | Human, Mouse, Rat, Zebrafish |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A synthesized peptide derived from human TDP43 |
| Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Predicted Protein Size | 45kDa |
| Gene Name | TAR DNA binding protein |
| Database Link | |
| Background | Swiss-Prot Acc.Q13148.TDP43 (TAR DNA-binding protein 43) is involved in transcriptional regulation and exon splicing. While normal TDP43 is a nuclear protein, pathological TDP43 is a component of insoluble aggregates in patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). |
| Synonyms | ALS10; TDP-43 |
| Reference Data | |
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