Thrombomodulin (THBD) Rabbit Polyclonal Antibody

CAT#: TA385404

Thrombomodulin Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human bladder, using Thrombomodulin Antibody.

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  Western blot analysis of Thrombomodulin expression in human placenta lysate.

Specifications

Product Data

• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Thrombomodulin
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 60kDa
• Gene Name: thrombomodulin
• Database Link:
  Entrez Gene 7056 Human
  UniProt ID P07204
• Background: Swiss-Prot Acc.P07204.Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
• Synonyms: AHUS6; CD141; fetomodulin; THRM; thrombomodulin; TM