TRIB3 Rabbit Polyclonal Antibody

CAT#: TA385459

TRIB3 Rabbit polyclonal Antibody

Product Images

Western blot analysis of TRIB3 expression in 293T cell lysate.

Specifications

Product Data

• Applications: IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IP: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human TRIB3
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 40kDa
• Gene Name: tribbles pseudokinase 3
• Database Link:
  Entrez Gene 57761 Human
  UniProt ID Q96RU7
• Background: Swiss-Prot Acc.Q96RU7.Disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. May bind directly to and mask the 'Thr-308' phosphorylation site in AKT1. Binds to ATF4 and inhibits its transcriptional activation activity. Interacts with the NF-kappa-B transactivator p65 RELA and inhibits its phosphorylation and thus its transcriptional activation activity.
• Synonyms: C20orf97; dJ1103G7.3; NIPK; SINK; SKIP3; TRB-3; TRB3