TXNRD1 Rabbit Polyclonal Antibody

CAT#: TA385501

Thioredoxin Reductase 1 Rabbit polyclonal Antibody

Product Images

Western blot analysis of TXNRD1 expression in (1) Jurkat cell lysate; (2) NIH/3T3 cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, IP, WB
• Recommended Dilution: WB: 1/500-1/2000
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  IP: 1/50
  FC: 1/120
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human TXNRD1
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 55kDa
• Gene Name: thioredoxin reductase 1
• Database Link:
  Entrez Gene 7296 Human
  UniProt ID Q16881
• Background: Swiss-Prot Acc.Q16881.Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
• Synonyms: GRIM-12; KDRF; MGC9145; oxidoreductase; TR; TR1; TRXR1; TXNR