TXNRD1 Rabbit Monoclonal Antibody [Clone ID: R01-8I4]

CAT#: TA385502

Thioredoxin Reductase 1 Rabbit monoclonal Antibody

Product Images

Western blot detection of TXNRD1 in K562,Hela cell lysates using TXNRD1 Rabbit mAb(1:1000 diluted).Predicted band size:67kDa.Observed band size:55kDa.

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  Immunohistochemistry of TXNRD1 in paraffin-embedded Human lung cancer tissue using TXNRD1 Rabbit mAb at dilution 1/20

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  Immunocytochemistry of TXNRD1(green) in Hela cells using TXNRD1 Rabbit mAb at dilution 1/5, and DAPI(blue)

Specifications

Product Data

• Clone Name: R01-8I4
• Applications: IF, IHC, IP, WB
• Recommended Dilution: WB: 1/1000-1/5000
  IHC: 1/20
  ICC/IF: 1/20-1/100
  IP: 1/20
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: Recombinant protein of human TXNRD1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 67 kDa; Observed MW: 55 kDa
• Gene Name: thioredoxin reductase 1
• Database Link:
  Entrez Gene 7296 Human
  UniProt ID Q16881
• Background: Swiss-Prot Acc.Q16881.Isoform 1 may possess glutaredoxin activity as well as thioredoxin reductase activity and induces actin and tubulin polymerization, leading to formation of cell membrane protrusions. Isoform 4 enhances the transcriptional activity of estrogen receptors alpha and beta while isoform 5 enhances the transcriptional activity of the beta receptor only. Isoform 5 also mediates cell death induced by a combination of interferon-beta and retinoic acid.
• Synonyms: GRIM-12; KDRF; MGC9145; oxidoreductase; TR; TR1; TRXR1; TXNR