Ubiquitin (UBB) Rabbit Polyclonal Antibody

CAT#: TA385511

Ubiquitin K48 Rabbit polyclonal Antibody

Product Images

Immunohistochemical analysis of paraffin-embedded human endometrium carcinoma, using K48-linkage Specific Ubiquitin Antibody.

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  Immunofluorescent analysis of MCF-7 cells, using K48-linkage Specific Ubiquitin Antibody.

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  Western blot analysis of Ubiquitin expression in Jurkat cell lysate.

Specifications

Product Data

• Applications: FC, IF, IHC, WB
• Recommended Dilution: WB: 1/100-1/500
  IHC: 1/50-1/200
  ICC/IF: 1/50-1/200
  FC: 1/50
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human K48-linkage Specific Ubiquitin
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Gene Name: ubiquitin B
• Database Link:
  Entrez Gene 7314 Human
  UniProt ID P0CG47
• Background: Swiss-Prot Acc.P0CG47.Plays an important role in the ubiquitin-proteasome pathway. Ubiquitin can be covalently linked to many cellular proteins by the ubiquitination process, which targets proteins for degradation by the 26S proteasome. Three components are involved in the target protein-ubiquitin conjugation process. Ubiquitin is first activated by forming a thiolester complex with the activation component E1; the activated ubiquitin is subsequently transferred to the ubiquitin-carrier protein E2, then from E2 to ubiquitin ligase E3 for final delivery to the epsilon-NH2 of the target protein lysine residue.
• Synonyms: FLJ25987; MGC8385; OTTHUMP00000064960; OTTHUMP00000064961; UBA80; UBCEP1; UBCEP2