VCAM1 Rabbit Monoclonal Antibody [Clone ID: R02-7H1]

CAT#: TA385539

VCAM1 Rabbit monoclonal Antibody

Product Images

Western blot detection of VCAM1 in 3T3 cell lysates using VCAM1 Rabbit mAb(1:1000 diluted).Predicted band size:81KDa.Observed band size:110KDa.

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  Immunohistochemistry of VCAM1 in paraffin-embedded Human tonsil using VCAM1 Rabbit mAb at dilution 1/100

Specifications

Product Data

• Clone Name: R02-7H1
• Applications: IHC, IP, WB
• Recommended Dilution: WB: 1/2000
  IHC: 1/20-1/500
  IP: 1/20
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Monoclonal
• Immunogen: A synthetic peptide of mouse VCAM1
• Formulation: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: Calculated MW: 81 kDa; Observed MW: 110 kDa
• Gene Name: vascular cell adhesion molecule 1
• Database Link:
  Entrez Gene 7412 Human
  UniProt ID P19320
• Background: Swiss-Prot Acc.P19320.Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
• Synonyms: CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561