WNT5A Rabbit Polyclonal Antibody
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Specifications
| Product Data | |
| Applications | FC, IF, WB |
| Recommended Dilution | WB: 1/500-1/1000 ICC/IF: 1/50-1/200 FC: 1/20 |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | A synthesized peptide derived from human Wnt5a |
| Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Concentration | lot specific |
| Purification | Affinity Chromatography |
| Conjugation | Unconjugated |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Stability | 1 year |
| Predicted Protein Size | 42kDa |
| Gene Name | Wnt family member 5A |
| Database Link | |
| Background | Swiss-Prot Acc.P41221.Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. |
| Synonyms | hWNT5A |
| Reference Data | |
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