WNT5A Rabbit Polyclonal Antibody

CAT#: TA385562

Wnt5a Rabbit polyclonal Antibody

Product Images

Western blot analysis of Wnt5a expression in HeLa cell lysate.

Specifications

Product Data

• Applications: FC, IF, WB
• Recommended Dilution: WB: 1/500-1/1000
  ICC/IF: 1/50-1/200
  FC: 1/20
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: A synthesized peptide derived from human Wnt5a
• Formulation: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
• Concentration: lot specific
• Purification: Affinity Chromatography
• Conjugation: Unconjugated
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Stability: 1 year
• Predicted Protein Size: 42kDa
• Gene Name: Wnt family member 5A
• Database Link:
  Entrez Gene 7474 Human
  UniProt ID P41221
• Background: Swiss-Prot Acc.P41221.Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression.
• Synonyms: hWNT5A