TNF alpha (TNF) Human Monoclonal Antibody [Clone ID: cA2 (Infliximab)]

CAT#: TA385751

Recombinant Anti-TNF alpha (Clone cA2 (Infliximab))

Product Images

Western Blot using anti-TNF alpha antibody Ab00146 Mouse liver (lane 1), mouse spinal cord (lane 2), mouse testis (lane 3), mouse colon (lane 4) and human thyroid tumour (lane 5) samples were resolved on a 10% SDS PAGE gel and blots probed with TA385751 at 1.5 µg/ml before being detected by a secondary antibody. The expected band size (26.9 kDa) is seen in the human-derived samples, as well as a band corresponding to dimers.

Specifications

Product Data

• Clone Name: cA2 (Infliximab)
• Applications: ELISA, FC
• Reactivities: Human
• Modifications: NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This is a chimeric antibody created for improved compatibility with existing reagents, assays and techniques.
• Host: Human
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Purified recombinant human TNF (rTNF).
• Specificity: Binds to soluble and transmembrane forms of TNF-alpha and neutralizes its biological activity. Does not bind to TNF-beta.
  
  This antibody can be used to detect and neutralize human TNF alpha. Unlike Adalimumab (Ab00718), Infliximab does not bind to mouse TNF alpha (Arnoult 2017, PMID: 28584008).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: tumor necrosis factor
• Database Link:
  Entrez Gene 7124 Human
  UniProt ID P01375
• Synonyms: Cachectin; DIF; TNF-a; TNF-alpha; TNFA; TNFSF2