TRP1 (TYRP1) Human Monoclonal Antibody [Clone ID: TA99]

CAT#: TA385800

Recombinant Anti-TRP-1, gp75 (Clone TA99)

Specifications

Product Data

• Clone Name: TA99
• Applications: ELISA, FC, IF, IHC, IP, WB
• Reactivities: Human
• Modifications: This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
• Host: Human
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: 70-75 kDa pigmentation-associated glycoprotein in human melanoma cell lines.
• Specificity: Binds Tyrosinase-related protein-1 (TRP-1), a 70-75k enzyme located in melanocytes, which are specialized cells that produce a pigment called melanin, helping to stabilize tyrosinase, which is the enzyme responsible for the first step in melanin production and determine the shape of melanosomes, which are the structures in melanocytes where melanin is produced.
  
  This antibody binds to human and murine TRP-1 and had been under evaluation for the treatment of tumours.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: tyrosinase related protein 1
• Database Link:
  Entrez Gene 7306 Human
  UniProt ID P17643
• Synonyms: b-PROTEIN; CAS2; CATB; GP75; TRP; TRP-1; TRP1; TYRP; TYRRP