IL2 Receptor alpha (IL2RA) Rabbit Monoclonal Antibody [Clone ID: Daclizumab]

CAT#: TA385811

Recombinant Anti-IL-2R (Clone Daclizumab)

Product Images

Flow-cytometry using the anti-CD25 (IL2R) research biosimilar antibody Daclizumab (Ab00187) Human lymphocytes were stained with an isotype control (Ab00102-23.0, panel A) or the rabbit-chimeric version of Daclizumab (TA385811, panel B) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FACSCanto flow-cytometer.

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  Flow-cytometry using anti-IL-2R antibody Daclizumab (Ab00187) Cynomolgus monkey lymphocytes were stained with an isotype control (Ab00102-23.0, red) or the rabbit-chimeric version of Daclizumab (TA385811, blue) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FlowJo single-cell flow cytometer.

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  Flow-cytometry using anti-IL-2R antibody Daclizumab (Ab00187) Rhesus monkey lymphocytes were stained with an isotype control (Ab00102-23.0, red) or the rabbit-chimeric version of Daclizumab (TA385811, blue) at a concentration of 1 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a AF488 conjugated donkey anti-rabbit antibody (ab150073) and cells analysed on a FlowJo single-cell flow cytometer.

Specifications

Product Data

• Clone Name: Daclizumab
• Applications: FC
• Reactivities: Human, Monkey
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: Cultured T-cells derived from a patient with Mycosis fungoides.
• Specificity: Binds to p55 chain of IL2R on human T cells, Tac antigen, which is expressed on T cells activated by mitogens, soluble antigens, and alloantigens but not on resting T cells, thymocytes, B cells, monocytes, activated B cells, leukemic T cell blasts from patients with acute lymphoblastic leukemia, and long-term T cell lines.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: interleukin 2 receptor subunit alpha
• Database Link:
  Entrez Gene 3559 Human
  UniProt ID P01589
• Synonyms: CD25; IDDM10; IL-2-RA; IL2-RA; IL2R; p55; TCGFR