CD4 Rabbit Monoclonal Antibody [Clone ID: MT310]

CAT#: TA385822

Recombinant Anti-CD4 (Clone MT310)


USD 523.00

2 Weeks*

Size
    • 200 ug

Product Images

Specifications

Product Data
Clone Name MT310
Applications FC, IF, IHC, IP, WB
Reactivities Human, Monkey
Modifications This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Host Rabbit
Isotype IgG, kappa
Clonality Monoclonal
Specificity mt310 binds to the extracellular domain D1 of CD4 – the same site as the HIV-1 gp120-binding site

mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-α (only after 20 h) and IL-10.
Formulation PBS with 0.02% Proclin 300.
Concentration lot specific
Conjugation Unconjugated
Storage Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Stability 3 years from dispatch.
Gene Name CD4 molecule
Synonyms CD4mut
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.