Cd28 Rabbit Monoclonal Antibody [Clone ID: JJ316]

CAT#: TA385860

Recombinant Anti-CD28 (Clone JJ316)

Specifications

Product Data

• Clone Name: JJ316
• Applications: FC, IF, IHC
• Reactivities: Rat
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: Made by immunizing BALB/c mice with rat CD28 cDNA-transfected A20/J cells.
• Specificity: Recognises rat CD28 and can trigger T-cell proliferation in vitro and in vivo.
  
  This antibody binds rat CD28 and can convey as a co-stimulatory signal. At 100-1000-fold higher concentration than required for co-stimulation JJ316 (unlike the clone JJ319 marketed by competitors (see Tacke et al. 1997)) can induce proliferation of all T-cell subsets without TCR engagement.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: Cd28 molecule
• Database Link:
  Entrez Gene 25660 Rat
  UniProt ID P31042
• Synonyms: MGC138290; Tp44