Cd28 Rabbit Monoclonal Antibody [Clone ID: D665]

CAT#: TA385862

Recombinant Anti-CD28 (Clone D665)

Specifications

Product Data

• Clone Name: D665
• Applications: FC, IHC
• Reactivities: Mouse
• Modifications: This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
• Host: Rabbit
• Isotype: IgG, kappa
• Clonality: Monoclonal
• Immunogen: The original D665 antibody was generated by immunizing mice alternately with A20 cells expressing mCD28 i.p. and with recombinant mCD28Ig s.c.
• Specificity: This antibody binds to the laterally exposed C′D loop of CD28 and induces T cell proliferation without TCR ligation.
  
  This antibody binds to mouse CD28. The original mouse IgG1 version was shown to trigger T-cell proliferation in vitro and in vivo in a TCR-independent manner and is a superagonistic antibody. This antibody does not compete with E18 (Ab00286).
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: CD28 antigen
• Database Link:
  Entrez Gene 12487 Mouse
  UniProt ID P31041
• Synonyms: MGC138290; Tp44