MCK10 (DDR1) Mouse Monoclonal Antibody [Clone ID: 3000]

CAT#: TA385957

Recombinant Anti-Discoidin Domain Receptor 1 (Clone 3E3)

Specifications

Product Data

• Clone Name: 3000
• Applications: Bl, ELISA, WB
• Reactivities: Human
• Modifications: This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Recombinant human DDR1 extracellular domain.
• Specificity: This antibody binds specifically to the extracellular domain of human DDR1.
  
  This antibody binds to human Discoidin Domain Receptor 1, a receptor tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates the attachemnt of the cell to the extracellular matrix. This receptor is required for blastocyst implantation during pregnancy, mammary gland differentiation as well as lactation. It promotes smooth muscle cell migration as well as tumour cell invasion. The antibody acts as an antagonist.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: discoidin domain receptor tyrosine kinase 1
• Database Link:
  Entrez Gene 780 Human
  UniProt ID Q08345
• Synonyms: CAK; CD167; DDR; EDDR1; HGK2; MCK-10; MCK10; NEP; NTRK4; OTTHUMP00000029344; OTTHUMP00000029345; OTTHUMP00000029346; OTTHUMP00000029347; PTK3; PTK3A; RTK6; TRKE