TrkA (NTRK1) Rabbit Monoclonal Antibody [Clone ID: MNAC13]

CAT#: TA385960

Recombinant Anti-TrkA (Clone MNAC13)


USD 523.00

2 Weeks*

Size
    • 200 ug

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Specifications

Product Data
Clone Name MNAC13
Applications Bl, ELISA, IHC
Reactivities Human
Modifications This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Host Rabbit
Isotype IgG, kappa
Clonality Monoclonal
Immunogen Human TrkA ECD.
Specificity This antibody binds to the extracellular domain of TrkA. It was shown not to cross react with TrkB . Moreover MNAC13 is specific to TrkA with negligible reactivity to TrkB and TrkC.

This antibody binds to human TrkA, a receptor tyrosine kinase involved in the development and the maturation of the CNS and the PNS through regulation of proliferation, differentiation, and survival of the sympathetic and nervous neurons. It is a receptor for NGF and phosphorylates several downstream proteins regulating a variety of signalling cascades. This antibody neutralizes the NGF-TrkA interation.
Formulation PBS with 0.02% Proclin 300.
Concentration lot specific
Conjugation Unconjugated
Storage Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Stability 3 years from dispatch.
Gene Name neurotrophic receptor tyrosine kinase 1
Synonyms DKFZp781I14186; MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.