CD11b (ITGAM) Mouse Monoclonal Antibody [Clone ID: 107]

CAT#: TA385978

Recombinant Anti-Integrin α-M (Clone 107)

Specifications

Product Data

• Clone Name: 107
• Applications: ELISA, FC
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1, kappa
• Clonality: Monoclonal
• Immunogen: Wild type (WT) recombinant CD11b.
• Specificity: This antibody binds to the MIDAS face of the A domain from integrin CD11b.
  
  The antibody binds specifically to integrin α-M, a protein subunit of the α-M- β-2 molecule, which is expressed on the surface of leukocytes. Integrin α-M is involved in the adhesive interaction between molecules of the innate immune system, and plays a role in the uptake of complement-coated particles. The monoclonal antibody 107 has a blocking activity by binding to the metal-ion-dependent-adhesion site, favouring a low affinity conformation of the antigen.
• Formulation: PBS with 0.02% Proclin 300.
• Concentration: lot specific
• Conjugation: Unconjugated
• Storage: Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
• Stability: 3 years from dispatch.
• Gene Name: integrin subunit alpha M
• Database Link:
  Entrez Gene 3684 Human
  UniProt ID P11215
• Synonyms: CD11B; CR3A; MAC-1; MAC1A; MGC117044; MO1A; SLEB6